4CMC

4CMC is no longer manufactured, we recommend Euthylone instead.

4CMC, also called 4-ChloroMethCathinone, is a novel Research Chemical from the substituted cathinone family. It is a strong dopamine and serotonine releaser without acting as reuptake inhibitor. It comes in large transparent crystals.

order 4cmc

gram	euro	per g
10	90	9	out of stock
25	200	8	out of stock
50	300	6	out of stock
100	550	5.5	out of stock
250	1000	4	out of stock
500	1600	3.2	out of stock
bulk:

Structure

The IUPAC of 4CMC is '1-(4-chlorophenyl)-2-(methylamino)propan-1-one', its CAS number is 2914790090.

Legality

This product must be legal in the destination country, or we won't accept the order. It is the customer's responsibility to conduct the necessary research regarding their local laws. Below you find a map that shows how we see the current situation regarding the legality of 4cmc, based on this documents.
If you think this data is incorrect, please email us about it. We only ship to green areas. We don't know about the grey areas. If you want a shipment to such a country, please provide us your local law-texts, and we will change color to green after a positive check.

Product description

4CMC, also known as Clephedrone, is a stimulant drug of the cathinone class that has been sold online as a designer drug.

Pharmacodynamics
In radioligand binding assays, 4-CMC had very low affinities of 9,410 nM, 28,700 nM, and 19,600 nM for the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET), respectively. In uptake potency assays, 4-CMC had low uptake potencies of 208 nM, 670 nM, and 75.5nM for the DAT, SERT, and NET, respectively. 4-CMC possessed full efficacy at stimulating the release of dopamine. The maximal response elicited by 4-CMC was 83.5% of the efficacy of methamphetamine. The maximal response elicited by 4-CMC was 124% of the maximal efficacy of methamphetamine. 4-CMC was more potent (EC50value = 1,980 nM) at stimulating release of serotonin compared to methamphetamine (27,500 nM).

AnimalStudies
In mouse locomotor activity assays, treatment with 2.5 to 10 mg/kg 4-CMC i.p. resulted in time-and dose-dependent increases in locomotion. Peak locomotor effects were observed following 5 mg/kg 4-CMC. Maximal locomotor stimulant effects of 5 mg/kg 4-CMC occurred 10-40 min post injection and lasted 70-230 min. Compared to cocaine, methamphetamine, and MDMA, the maximal stimulant effectsof 4-CMC were 66%, 63% and 64%, respectively. In drug discrimination assays, 4-CMC i.p. fully substituted (ED50= 4.3mg/kg) for the discriminative stimulus effects of 10 mg/kg, i.p. cocaine in rats. 4-CMC also fully substituted (ED50= 3.9mg/kg) for the discriminative stimulus effects of 1.0mg/kg, i.p.(+)-methamphetamine.

Quality
We make 4CMC at our own lab. Crystals are trasparent and huge, see image below. It has a purity over 99%. Please store sealed. For long term storage keep at -20 degree. Durability is 7 years.

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